A few people have recently asked me: Should I use Drupal 5 or Drupal 6?
Drupal 6 is stable and it has a lot of great features that aren't available in Drupal 5. The only reason I would use Drupal 5 for a new site is if using a module that were only available for Drupal 5. Ubercart is one that comes to mind. (I haven't used Ubercart, but it was recommended to me as the ideal way to to ecommerce in Drupal.)
Drupal 6 is great. There's no reason not to use it except if there is a module that isn't available yet. I can't think of any modules that I use on a regular basis that aren't available for Drupal 6.
Drupal 6 gives you things like:
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